Saturday, June 20, 2009

The Effect of Knowledge on Adherence to Hypertensive Medication

Given that knowledge is likely to affect an individual’s ability to be adherent with therapy, researchers have investigated the effect of the amount and type of knowledge of 227 hypertensive patients on their medication-taking habits. Researchers found that 72% (163) were adherent and 28% (64) were non-adherent and that the type of knowledge patients had greatly affected their adherence. Knowing the duration of use of the medicine (OR=6.822; p=0.075), the reason for taking the medication (OR-2.828; p=0.018), the cause of hypertension (OR-3.447; p=0.037), and knowing the target blood pressure level (OR-12.859; p<0.001) increased adherence rates. Further, knowing the name (p=0.112) or the results of hypertension (p=0.719) had no effect, whereas knowing the side-effects had a negative effect on adherence (OR=0.607; p=0.005). See also the recently published article by Murray et al. demonstrating the association between poor health literacy and adherence, and the exacerbation of heart failure.